Could Translational Research Approach Lead to Kidney Disease Treatment?

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Dr. Doria (left) and Dr. Krolewski (right)

This article was originally posted on March 31, 2014.

The complexities of diabetes can’t be fully understood in a lab or in a clinic alone. Sometimes, information coming from the lab informs clinical researchers about what they should study in people with diabetes. Other times, trends noticed in patient visits can lead to an important study at the bench.

The back-and-forth, cross-disciplinary nature of diabetes research and medical research in general is known as translational research.

“It is a reciprocal journey from initial observation in lab or clinic to understanding the relevance of the finding to patients, practice and population health,” said Allison Goldfine, M.D., Head of the Section on Clinical, Behavioral and Outcomes Research.

Joslin Diabetes Center is dedicated to translational research; so much so that Joslin will soon open the doors to the newly constructed Translational Research Center for the Cure of Diabetes. This center will improve communication and encourage collaboration between basic science researchers and clinical researchers.

But Joslin hasn’t been waiting for the Translational Center’s unveiling to do this type of important work. Translational research has been part of Joslin’s approach to understanding more about diabetes for years. Continue reading –>

6 Responses to Could Translational Research Approach Lead to Kidney Disease Treatment?

  1. phusa ram says:

    Me at 65 ,non diabetic,goutyUA above 7 mg/DL ,used fuboxtat 40 ,since one last year,recently ,my test read6.22 ,and gp advised to stop fuboxtat ,two weeks later ,flare up ( mild) in 1st smaller toe reappeared ,I ,a follower of gout pal forum ,knew about allupurinol , so ,since last 2 days ,am on allupurinol 100 MD for next 6 moths ,
    Am I wrong or right ,kindly advise ?

    • roger goertemiller says:

      i have kidney disease ,gfr 22. also diabetic. i also take allupurinol for years(gout). ihave just recenty started with tis kidney problem. thank you

  2. Beverly Melvin says:

    Do you have any information about managing type II diabetes in the presence of MDS Refractory Anemia with a number of chromosomal abnormalities? Does low hemoglobin affect the out come of HbA1c tests?

  3. Vikram says:

    Kidney stones are a painful reality for many people, but there are many natural remedies one can use to help himself get rid of kidney stones and prevent their re-occurrence in the future.

  4. tuhumom says:

    Very interesting discussion. As a former kidney disease sufferer, I know how frustrating it can be to find answers. Just wanted to share a link that helped me out a lot when I was struggling to get better:

    Best of luck to everyone!

  5. Since homocystein is suspected to cause epithelial degradation, the reduction of HC may allow the tissue to regenerate..Enlyte is a RX drug that utilizes the bioactive metabolites of the B vitamins to lower HC.

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