Does a nutrient found in beets reduce diabetes risk?

Description: In this clinical research study we are evaluating whether supplementation of a naturally occurring component found in beets and other vegetables and grains reduces diabetes risk. The product we are studying is a modified amino acid that is important in several metabolic pathways and lower in patients with diabetes and cardiovascular risk factors.

Participants will have a glucose tolerance test, commonly used to diagnose type 2 diabetes and if prediabetic will be randomized (like the flip of a coin) to receive the supplement or a placebo. Measurements of insulin sensitivity, liver fat, and blood vessel function will occur before and after 3 months of supplementation, requiring two days at the start and again at the end of the study with two additional morning visits during the study.

Recruiting: We are seeking clinical Research Volunteers with risk factors for type 2 diabetes or pre-diabetes who are overweight, between 21-65 years of age, who are willing to help us learn about the effects of naturally occurring food substances on cardiometabolic health.

Contact: If you are interested in learning more about the study, please contact the METABOLIC EFFECTS OF BETAINE SUPPLEMENTATION study fellow Ana Maria Grizales at 617-309-4736 or email ana.grizales@joslin.harvard.edu

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