SLIMM T2D Study: Surgery of Lifestyle with Intensive Medical Management in the treatment of Type 2 Diabetes

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Description: We are comparing whether bariatric surgery (weight loss surgery) or a diabetes and intensive medical and weight management program is more effective for the treatment of type 2 diabetes in patients who are modestly overweight.

Participants will be randomized (like the flip of a coin) to surgical or non-surgical treatment.

Participants randomized to surgery will have their surgery performed at the Brigham and Women’s Hospital, Boston.  Follow up visits for surgical groups can vary based on the type of surgery performed.

Those participants randomized to the Intensive Medical Management program will have several visits at the Joslin Diabetes Center, Boston which include the following:

  • Weekly evening meetings over 13 weeks for group education and support led by a physician, diabetes nurse educator, nutritionist, exercise physiologist and behavior counselor
  • Monthly follow up visits after 13 weeks

Both surgial and non-surgical groups are followed over three years.

Recruiting: We ae seeking clinical Research Volunteers with type 2 diabetes and excess weight, between 21-65 years of age, who are willing to have bariatric (weight loss) surgery or participate in an intensive medical (non-surgical) diabetes and weight management program.

Contact: Kerri Clancy at 617-525-7388  or email SLIMMT2D@Partners.Org

13 Responses to SLIMM T2D Study: Surgery of Lifestyle with Intensive Medical Management in the treatment of Type 2 Diabetes

  1. Beverly Romasco says:

    I am a 66 year old lady with type 2 diabetes and really would like to be considered for this program…….I lost 30 lbs on my own, but I know I have gained probably half of it back…..i really would like to be considered…….I hope that you will

  2. Christine Davidson says:

    I am 65 with type 2 and about 100lbs overweight and I am willing to either have surgery or intensive help. Thanks. Chris

    • Hi Christine! Did you ever get a response on this? If not, I’m sorry it has taken someone this long to get back to you. If you are still interested in being considered for the study, please get in touch with Kerri Clancy (phone: 617-525-7388 or email: SLIMMT2D@Partners.Org). Kerri will be able to give you more information and determine if you are eligible!

      Thank you for your interest

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  6. CJ says:

    My question is.. Can I particapate in the SLIMM T2D program if I live in another state? I would be very interested in the intensive program. I am 55 and I need to loose 150 lbs. last year I lost 75 lbs due to a few different reasons, but I have gained back 45 lbs. I don’t really know how I managed to do that. I have been eating the same way and the amount of food is the same if not less now than before. However, I have been on several defferent medications and different insulins in the past 1 + years. I would love to learn more about the program and how I may be seected to particapate. Thank you for your time regarding this matter.

    • Hi CJ,

      In order to participate in the SLIMM-T2D trial you need to be willing to commit to your diabetes and weight management, either through bariatric surgery called laparoscopic adjustable gastric band, or through the intensive diabetes and weight management program that involves a 3-month series of weekly meetings held in the evenings at the Joslin Diabetes Center in Boston. If you are interested in learning more, please contact Kerri Clancy at 617-525-7388 or email SLIMMT2D@Partners.Org. We will review individually with you the details of the study and whether you are a candidate for our study.

      We hope to have the opportunity to work with you!
      Dr. Allison Goldfine

  7. Judith Cox says:

    I would like to be considered. I am a 70 year old female and have been diabetic for 22 years, I currently wear an insulin pump. I am being considered for bariatric surgery here in NYC at NYU.

    Please let me know if I would be a candidate for your program/study?

    Thank you,

    • Hi Judith,

      Thank you for your interest in our study. Unfortunately our study involves patients between 21 and 65 years of age, thus at 70 years old, you would not be able to participate. In addition, the intensive medical management program involves a 3-month series of weekly meetings held in the evenings at the Joslin Diabetes Center in Boston, which could be difficult for you to attend if you were to be coming from New York City.

      You should continue to speak to your doctors about your treatment, as bariatric surgery and medical management of your diabetes are available as part of clinical care outside of clinical research studies.

      Thanks for getting touch,
      Dr. Allison Goldfine

  8. Tyrin Avery says:

    I think this is a very badly designed study. For one thing, the only people who will sign up for it are people who are willing (wanting) to undergo surgery. That let’s out me, for example, even though I might otherwise be a good target for intervention. Secondly, the medicallly-intensive program you have designed seems to have the same flaws that the existing Joslin programs have 1) geographically limited, 2) requiring people to completely rearrange their live, take off work etc to attend 3) medically top-down, where the diabetics are sternly instructed, rather than helping people problem-solve issues with their treatment.
    Honestly, I wish they would do a program where I had to check in online once a week and report my numbers. Where I could ask questions of doctors and other patients about how they solve problems – like how do they remember to take their meds, how do they find canoes/bikes/sports equipment and clothing for larger people, how do they manage med side effects. These are all the things that are tripping me up.

    • We appreciate your concerns and understand that our study is not for everyone. Often research studies begin with a defined clinical question and a limited group of patients. How to expand clinical initial findings into a broader “real world” setting is a second step.

      In the SLIMM-T2D study, we seek to understand how bariatric surgery compares to an intensive diabetes and weight management program. We would never consider randomizing patients who would consider only one but not the other treatment option. We recognize that only people who live close enough to attend the 3 months of weekly sessions will be able to participate in the study and that many others will not be able to get time from work or for other personal commitments.

      To address your other questions, there are ongoing online sites you may access to problem solve with others, such as the Joslin Message Boards (, which are monitored by Joslin physicians and staff. You can also connect with other people with diabetes at the Joslin Facebook page (, or by starting discussions on Twitter with the hashtag #dsma. The ADA also has message boards here:

      –Dr. Allison Goldfine

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